Transdifferentiation, Metaplasia and Tissue Regeneration

Pulp and periodontal tissue repair - regeneration or tissue metaplasia after dental trauma. A review.

Healing subsequent to dental trauma is known to be very complex, a result explained by the variability of the types of dental trauma (six luxations, nine fracture types, and their combinations). On top of that, at least 16 different cellular systems get involved in more severe trauma types each of them with a different potential for healing with repair, i.e. (re-establishment of tissue continui...

PAR2 regulates regeneration, transdifferentiation, and death

Understanding the mechanisms by which cells sense and respond to injury is central to developing therapies to enhance tissue regeneration. Previously, we showed that pancreatic injury consisting of acinar cell damage+β-cell ablation led to islet cell transdifferentiation. Here, we report that the molecular mechanism for this requires activating protease-activated receptor-2 (PAR2), a G-protein-...

Liver Regeneration, Stem Cells and Transdifferentiation

Regeneration of the amphibian retina: role of tissue interaction and related signaling molecules on RPE transdifferentiation.

Regeneration of eye tissue is one of the classic subjects in developmental biology and it is now being vigorously studied to reveal the cellular and molecular mechanisms involved. Although many experimental animal models have been studied, there may be a common basic mechanism that governs retinal regeneration. This can also control ocular development, suggesting the existence of a common princ...

معرفی درمان ضایعات استخوانی توسط روش guided tissue regeneration

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